MALDI-TOF Laser Installed at the Hoag Family Cancer Institute Translational Lab
Hoag Innovators-funded technology allows Hoag’s precision medicine team to identify markers of cancer recurrence or growth sooner than traditional methods.
Funded by Hoag Innovators in spring 2021, the Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) is now located in the Innovators-funded Translational Lab for maximum utilization by the Hoag Family Cancer Institute’s clinical research team. The MALDI-TOF laser provides analysis of the protein content of exosomes, small vesicles produced by cancer cells that contain DNA, RNA, microRNA, lipids, and proteins. What makes this protein analysis so valuable to Hoag’s precision medicine team, led by Dr. Michael Demeure, Otis Healy Family Endowed Chair in Applied Genomics, is that it allows for the development of personalized protein signatures and real-time samples that identify spikes in protein indicative of cancer recurrence or growth sooner than traditional methods.
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